Pleiotropy

Pleiotropy and Cross-Disorder Genetics Among Psychiatric Disorders

Genome-wide analyses of common and rare genetic variations have documented the heritability of major psychiatric disorders, established …

Lee, P. H., Feng, Y. A., & Smoller, J. W.

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. …

Lee, P. H., Anttila, V., Won, H., Feng, Y. A., Rosenthal, J., Zhu, Z., ..., Smoller, J. W. (Cross-Disorder Group of the Psychiatric Genomics Consortium)